Dr. Levy works at the interface of epidemiology, ecology and statistics to understand and control vector-borne and other infectious diseases. For nearly two decades he has focused his research on the control of urban Chagas disease transmission in Peru. His research team in Peru conducts epidemiological studies on Chagas disease as well as entomological and ecological research on disease vectors and reservoirs. In addition, his team uses quantitative and qualitative methods to elucidate the factors that have led to the urbanization of a disease traditionally associated with rural poverty.

In the United States Dr. Levy focuses on Bed bugs and housing policy, work which has segued into studies on eviction, housing security and the transmission of SARS-CoV-2.

Dr. Levy's methodological interests include developing new methods to make inference on infectious disease dynanics and to improve interventions against dangerous insects.