Dr. Zee’s research focuses on developing and applying methods for observational and survival data analysis and identifying novel biomarkers of kidney disease progression. She collaborates on clinical research projects in glomerular disease and chronic kidney disease, including topics in genotype-phenotype data integration, analysis of electronic health records, pathology imaging, comparative treatment effectiveness, surrogate endpoints, and patient-centered outcomes. She also has additional clinical interests in women’s health, pediatric skeletal health, and cardiovascular disease.  

Dr. Zee joined the biostatistics faculty at the University of Pennsylvania and the Children’s Hospital of Philadelphia (CHOP) Research Institute in 2020. Prior to her work at Penn and CHOP, she was a Research Scientist at Arbor Research Collaborative for Health in Ann Arbor, Michigan. She is a co-principal investigator on an NIH/NIDDK-funded study on computational pathology for proteinuric glomerulopathies, which uses computational approaches to identify new imaging markers of clinical outcomes. She is also principal investigator of a NIH/NIDDK-funded P50 research project to develop marginal structural models for estimating time-varying treatment effects on recurrent event outcomes. She brings strong experience with data coordinating centers, including serving in her current role as a co-investigator for the Data Analysis and Coordinating Center for the Nephrotic Syndrome Study Network (NEPTUNE).